The invention provides a plug-separable type multi-directional power supply which comprises a body with an insertion connection space and two conduction connection terminals exposed to the insertion connection space in a protruding mode. A plug is combined on the body and comprises a seat body with a containing space. Two conduction connection pieces are arranged in the containing space oppositely, a positioning cover is combined on the body and covers on the containing space, and two guide grooves corresponding to the two conduction connection terminals are arranged on the positioning cover. A brake ring piece is arranged between the two conduction connection pieces and the positioning cover, and a plurality of positioning grooves corresponding to the two guide grooves are arranged on the inner edge of the brake ring piece. The plug can rotate in multiple directions on the body, and the two conduction connection terminals slide in the two guide grooves respectively to be positioned in the positioning grooves and are connected with the two conduction connection pieces in a conducting mode correspondingly. Insertion connection directions of the power supply are easy to change.