Bicyclol solid preparation and preparation method thereof



The invention discloses a bicyclol solid preparation and a preparation method of the bicyclol solid preparation. Because the bicyclol is a slightly soluble drug, the bicyclol is treated by adopting a micronization mode, and the particle size is reduced. The main drug bicyclol, a filling agent and a solubilizer are combined, ground and micronized, the micronization difficulty is reduced, the dissolution effect is good, the bioavailability is high, and the bicyclol solid preparation is simple and convenient in operation and stable in process.




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    储茂泉等: "丹参酮-预胶化淀粉共研磨混合物的研究", 《中国现代应用药学杂志》, vol. 18, no. 5, 31 October 2001 (2001-10-31), pages 359 - 362

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